During a visit to Transylvania, an African prince (William Marshall) gets turned into a vampire by Count Dracula (Charles Macaulay). Sealed in a coffin for several lifetimes, "Blacula" reawakens in 1970s Los Angeles. Leaving a trail of bloodless victims in his wake, he pursues Lina (Vonetta McGee), a woman who bears a striking resemblance to his dead wife. Meanwhile, Dr. Gordon Thomas (Thalmus Rasulala) and top cop Lt. Peters (Gordon Pinsent) are hot on the bloodsucker's trail.