Intrepid archaeologist Indiana Jones, on the trail of fortune and glory in Old Shanghai, is ricocheted into a dangerous adventure in India. With his faithful companion Short Round and nightclub singer Willie Scott, Indy goes in search of a mystical stone, and uncovers an ancient evil which threatens all who come into contact with it.

The intrepid explorer Indiana Jones sets out to rescue his father, a medievalist who has vanished while searching for the Holy Grail. Following clues in the old man's notebook, Indy arrives in Venice, where he enlists the help of a beautiful academic, but they are not the only ones who are on the trail, and some sinister old enemies soon come out of the woodwork.