Estranged brothers Francis (Owen Wilson), Peter (Adrien Brody) and Jack (Jason Schwartzman) reunite for a train trip across India. The siblings have not spoken in over a year, ever since their father passed away. Francis is recovering from a motorcycle accident, Peter cannot cope with his wife's pregnancy, and Jack cannot get over his ex-lover. The brothers fall into old patterns of behaviour as Francis reveals the real reason for the reunion: to visit their mother in a Himalayan convent.

Shows with Hotel Chevalier – the 13-minute short that acts as a prologue to The Darjeeling Limited.

In the 1930s, the Grand Budapest Hotel is a popular European ski resort, presided over by concierge Gustave H. (Ralph Fiennes). Zero, a junior lobby boy, becomes Gustave's friend and protege. Gustave prides himself on providing first-class service to the hotel's guests, including satisfying the sexual needs of the many elderly women who stay there. When one of Gustave's lovers dies mysteriously, Gustave finds himself the recipient of a priceless painting and the chief suspect in her murder.