Jodie Foster stars as Clarice Starling, a top student at the FBI's training academy. Jack Crawford (Scott Glenn) wants Clarice to interview Dr. Hannibal Lecter (Anthony Hopkins), a brilliant psychiatrist who is also a violent psychopath, serving life behind bars for various acts of murder and cannibalism. Crawford believes that Lecter may have insight into a case and that Starling, as an attractive young woman, may be just the bait to draw him out.

It took Anna (Nicole Kidman) 10 years to recover from the death of her husband, Sean, but now she's on the verge of marrying her boyfriend, Joseph (Danny Huston), and finally moving on. However, on the night of her engagement party, a young boy named Sean (Cameron Bright) turns up, saying he is her dead husband reincarnated. At first she ignores the child, but his knowledge of her former husband's life is uncanny, leading her to believe that he might be telling the truth.