Keller Dover (Hugh Jackman) faces a parent's worst nightmare when his 6-year-old daughter, Anna, and her friend go missing. The only lead is an old motorhome that had been parked on their street. The head of the investigation, Detective Loki (Jake Gyllenhaal), arrests the driver (Paul Dano), but a lack of evidence forces Loki to release his only suspect. Dover, knowing that his daughter's life is at stake, decides that he has no choice but to take matters into his own hands.

When he is not planning for his upcoming stage musical or working on his Hollywood film, choreographer/director Joe Gideon (Roy Scheider) is popping pills and sleeping with a seemingly endless line of women. The physical and mental stress begins to take a toll on the ragged perfectionist. Soon, he must decide whether or not his non-stop work schedule and hedonistic lifestyle are worth risking his life. The film is a semi-autobiographical tale written and directed by the legendary Bob Fosse.